Modern Life Pushes Your Brain Harder Than Ever.
9 Ingredients. Optimally Dosed.
We don’t just include what works. We include what works together. Each compound is in its most absorbable form, selected to enhance the effectiveness of the others. Engineered for performance. Built for resilience.
100mg Phosphatidylserine
Studied for its role in memory, cognitive function, and stress response.
1.3mg P5P (B6)
Supports neurotransmitter function and contributes to normal psychological function.
1000mg Lion's Mane (Fruiting Body)
Studied for its effects on nerve growth factors and brain function.
500mg L-Tyrosine
Included for its role in cognitive performance and mental focus during demanding tasks.
200mg L-Theanine
Supports calm focus and has been studied for its role in stress response.
250mg Citicoline
Clinically studied for cognitive function and attention.
160mg Bacopa Monnieri
Traditionally used in Ayurvedic medicine and studied for its role in memory and mental clarity.
400μg B12 Methylcobalamin
Contributes to normal energy metabolism and nervous system function.
400μg 5‑MTHF
Supports methylation and cognitive health.
100mg Phosphatidylserine
Supports Cognitive Function & Memory
Phosphatidylserine is essential for supporting memory, focus, and cognitive function. As a key phospholipid found in brain cell membranes, it plays a crucial role in maintaining neuronal integrity and facilitating communication between brain cells. Research has shown that PS supplementation may help support memory recall, learning performance, and mental clarity, particularly in older adults experiencing age-related cognitive changes. By contributing to brain plasticity, PS helps the brain adapt, form new connections, and retain information. Several clinical studies have demonstrated that consistent PS supplementation may help maintain memory and support long-term cognitive performance.
Supports Attention & Focus
Struggling with focus and mental fatigue? Phosphatidylserine may help support mental clarity and engagement for longer periods. Research indicates that PS may influence dopamine pathways and neurotransmitter activity, which are essential for concentration, sustained attention, and cognitive endurance. It has also been studied for its potential to support reaction time and decision-making speed, making it a valuable compound for professionals, students, and anyone looking to maintain high levels of focus. In studies, individuals taking PS reported better attention span and reduced cognitive fatigue in high-demand environments like work, study, and competitive sports.
Supports Stress Response & Cortisol Regulation
Chronic stress can impact brain function, contributing to fatigue, burnout, and reduced mental performance. Phosphatidylserine has been studied for its potential to modulate cortisol, the body’s primary stress hormone. By supporting a balanced stress response, PS may promote emotional stability and help the brain perform under pressure. Clinical research suggests that individuals supplementing with PS experienced lower stress-related cortisol levels and reported feeling more mentally resilient. Whether you are managing a demanding job, balancing responsibilities, or operating in high-stress situations, PS can help support mental clarity and composure.
Studied for Performance & Recovery
Beyond its cognitive role, Phosphatidylserine has been researched for its potential benefits in physical performance, endurance, and post-exercise recovery. Several studies suggest that PS may support reduced post-exercise muscle soreness and aid recovery after intense training. These effects are believed to be related to its influence on cortisol levels, which can rise during prolonged physical exertion and contribute to fatigue. In trials, athletes supplementing with PS reported improved endurance, better reaction times, and reduced fatigue following exercise. For active individuals, PS may be a valuable tool to support performance and recovery.
Supports Long-Term Brain Health
As we age, cognitive changes can affect memory and brain function. Phosphatidylserine plays a structural role in brain cells and may help protect against oxidative stress, a key factor in maintaining long-term brain health. Research suggests that regular PS supplementation may help support cognitive function in older adults. Although more evidence is needed, some studies have explored its potential to help preserve brain function and slow cognitive decline. By supporting neural pathways and overall brain structure, PS contributes to sustained mental performance with age.
References
| Cenacchi et al. (1993) | 6‑month placebo‑controlled trial in 494 elderly individuals with age‑related cognitive decline; improved memory, learning ability, and daily function with 300 mg/day of PS from bovine cortex. DOI: 10.1007/BF02253177 |
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| Kato‑Kataoka et al. (2010) | 6‑month study on Japanese adults with mild memory complaints; 300 mg/day of soy‑derived PS improved episodic memory and word recall. DOI: 10.1248/bpb.33.1511 |
| Vakhapova et al. (2010) | 15‑week randomized controlled trial on elderly participants with memory complaints; 300 mg/day of DHA‑enriched PS improved verbal recall and working memory. DOI: 10.3233/JAD-2010-1342 |
| Hellhammer et al. (2004) | Placebo‑controlled study on 132 healthy young adults under stress conditions; 400 mg/day of soy‑derived PS significantly reduced cortisol responses and improved stress resilience. DOI: 10.1016/j.steroids.2004.02.012 |
| Parker et al. (2011) | Study on male athletes under cognitive stress; 400 mg/day of soy‑derived PS for 2 weeks improved cognitive performance, mood, and focus under stress. DOI: 10.1136/bjsm.2010.081885.26 |
| Cleveland Clinic | Clinical overview on phosphatidylserine’s role in reducing stress and improving mood. Source: MY.CLEVELANDCLINIC.ORG |
| Hirayama et al. (2014) | Study on healthy children assessing attention span and cognitive performance; 200 mg/day of PS for 2 months improved sustained attention, learning performance, and processing speed. DOI: 10.1016/j.nut.2014.02.008 |
| Crook et al. (1992) | 12‑week randomized controlled trial on individuals with cognitive impairments; 300 mg/day of bovine‑derived PS improved focus and learning ability. DOI: 10.3233/JAD-1992-424 |
| Grieb et al. (2014) | Long‑term study assessing age‑related cognitive decline; PS supplementation preserved brain membrane function, slowing cognitive deterioration. DOI: 10.3390/ijms15069649 |
| Kingsley et al. (2006) | Study on resistance‑trained athletes performing high‑intensity exercise; 750 mg/day of soy‑derived PS for 10 days reduced muscle soreness and improved recovery time. DOI: 10.1136/bjsm.2005.023630 |
| Starks et al. (2008) | Placebo‑controlled trial on male athletes; 600 mg/day of PS for 10 days enhanced endurance and reaction time in high‑intensity exercise. DOI: 10.1097/JSM.0b013e31815f51d1 |
| GRC | Research compilation on phosphatidylserine’s role in exercise recovery, reducing muscle soreness, and performance optimization. Source: GRC.COM |
1.3mg P5P (B6)
Supports Cognitive Function & Brain Health
P5P is the active form of vitamin B6 and plays an important role in normal brain function. It contributes to the production of key neurotransmitters including serotonin, dopamine, and GABA, which are involved in learning, memory, and mental clarity. P5P also supports the regulation of homocysteine levels, a biomarker associated with metabolic and cognitive function. By contributing to normal psychological function and energy metabolism, P5P plays a supportive role in maintaining attention, processing speed, and overall cognitive performance.
Contributes to Psychological Balance
Vitamin B6 is involved in the synthesis of neurotransmitters that support mood regulation. Research has linked adequate B6 levels to better emotional balance, particularly in relation to workload-related stress and general well-being. P5P has been studied for its influence on cortisol and other stress-related markers. While individual responses vary, some evidence suggests that active vitamin B6 may help support mental clarity and composure in demanding situations.
Supports Energy Production & Reduces Tiredness
P5P is an essential coenzyme in energy metabolism, helping to convert carbohydrates, proteins, and fats into usable energy. It also contributes to the normal formation of red blood cells, which play a role in oxygen transport and energy availability throughout the body. Clinical studies have shown that maintaining optimal B6 levels may support physical and mental stamina, reduce fatigue, and improve cognitive endurance during long periods of concentration or physical effort.
Supports Homocysteine Metabolism & Circulatory Function
Vitamin B6 plays a central role in the normal metabolism of homocysteine — an amino acid whose regulation is associated with vascular health. Balanced homocysteine levels are important for cardiovascular and neurological function. While more research is ongoing, some studies have associated adequate B6 status with healthy circulation and oxygen delivery, both of which contribute to brain and cardiovascular performance.
Contributes to Immune Health & Cellular Defence
Vitamin B6 is required for the function of the immune system, including the production of white blood cells and immune signalling molecules. As P5P, it also plays a role in maintaining normal inflammatory responses and supporting antioxidant defence systems. These functions help protect cells from oxidative stress — a key factor in cellular ageing and long-term health. Maintaining adequate vitamin B6 levels may help support immune resilience and general wellbeing over time.
References
| Nyaradi et al. (2013) | Higher P5P levels in adolescents were correlated with better cognitive performance in memory, learning, and executive function. DOI: 10.3945/ajcn.113.064261 |
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| Garcia et al. (2021) | Supplementing with P5P improved working memory and verbal learning in middle-aged adults at risk for cognitive decline. DOI: 10.1016/j.jnutbio.2021.108856 |
| Spinneker et al. (2007) | Vitamin B6 deficiency linked to poor cognitive function, suggesting optimal P5P levels are necessary for brain health. DOI: 10.1016/j.nut.2006.12.007 |
| Hvas et al. (2004) | Higher B6 levels were associated with lower depression and anxiety symptoms in elderly adults. DOI: 10.1016/j.psyneuen.2004.07.007 |
| Moore et al. (2022) | Supplementation with P5P significantly reduced stress and anxiety symptoms in young adults. DOI: 10.3390/nu14091952 |
| Hussain et al. (2018) | Improved mood and reduced irritability were observed in individuals supplementing with P5P. DOI: 10.3390/nu10030381 |
| Kennedy et al. (2010) | Improved mental and physical energy following vitamin B6 supplementation in fatigued individuals. DOI: 10.1016/j.pbb.2010.02.005 |
| McCann et al. (2016) | P5P deficiency was associated with higher fatigue levels and lower energy metabolism in elderly populations. DOI: 10.3945/an.115.009316 |
| Bryan et al. (2002) | Improved reaction times and reduced mental fatigue with vitamin B6 supplementation. DOI: 10.1016/S0195-6663(02)00235-6 |
| Finkelstein et al. (2013) | P5P supplementation significantly reduced homocysteine, lowering cardiovascular risk. DOI: 10.3945/ajcn.113.064469 |
| Kelly et al. (2017) | Lower B6 levels correlated with a higher risk of heart disease, indicating supplementation may be beneficial. DOI: 10.1016/j.nut.2017.01.005 |
| Van Oort et al. (2003) | B6 supplementation reduced arterial stiffness and improved vascular health. DOI: 10.1038/ejcn.2003.101 |
| Meyer et al. (2020) | P5P supplementation enhanced immune response and reduced inflammation in elderly individuals. DOI: 10.3390/nu12010015 |
| Ueland et al. (2015) | Vitamin B6 deficiency linked to increased inflammation and weakened immune function. DOI: 10.1016/j.clnu.2015.06.001 |
| Chiba et al. (2021) | Supplementation improved immune cell activity and reduced oxidative stress. DOI: 10.1016/j.jnutbio.2021.108945 |
1000mg Lion's Mane
Supports Cognitive Function & Memory
Lion’s Mane is a medicinal mushroom studied for its potential to support memory, focus, and overall cognitive performance. Some clinical studies suggest it may help maintain learning ability, recall, and mental clarity, particularly in adults experiencing mild age-related cognitive changes. These effects are believed to be linked to Lion’s Mane’s role in stimulating Nerve Growth Factor (NGF), a protein involved in the maintenance and regeneration of neurons. NGF supports brain cell health and communication between neurons, contributing to cognitive resilience as we age.
Supports Mood & Emotional Wellbeing
Lion’s Mane has been investigated for its influence on mental wellbeing. It may support mood balance by interacting with pathways related to NGF and Brain-Derived Neurotrophic Factor (BDNF), two neurotrophins associated with brain plasticity and emotional health. Some preliminary studies also suggest that Lion’s Mane may modulate neurotransmitters such as serotonin and dopamine, which are involved in emotional regulation and motivation. In small human trials, participants reported improvements in mood-related measures following regular supplementation.
May Help with Stress Resilience & Mental Clarity
Research indicates that Lion’s Mane may support the brain’s ability to adapt to stress. By influencing neurotrophic signalling and the body’s natural stress response systems, Lion’s Mane has been studied for its potential to help maintain clarity and performance under pressure. Some evidence suggests it may contribute to the balance of stress hormones such as cortisol, and support regions of the brain associated with memory and emotional regulation.
Supports Long-Term Brain Health
Lion’s Mane is being explored for its potential to support long-term brain function through its effects on NGF, BDNF, and antioxidant activity. These mechanisms are believed to contribute to neuronal maintenance and protection against oxidative stress — two key factors in cognitive ageing. While more research is needed, early studies have focused on Lion’s Mane’s possible role in sustaining brain structure and function into later life.
Contributes to Gut-Brain Axis Support
Emerging research suggests that the gut microbiome can influence cognitive and emotional health through what is known as the gut-brain axis. Lion’s Mane has been studied for its potential to promote the growth of beneficial gut bacteria and support intestinal barrier function. These effects may contribute to broader wellbeing by supporting healthy digestion and gut-based neurotransmitter production, including serotonin — much of which is produced in the gut.
References
| Mori et al. (2009) | 16‑week placebo‑controlled trial in MCI patients showed significant cognitive improvements; effects reversed when supplementation stopped. DOI: 10.1002/ptr.2634 |
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| Li et al. (2020) | Alzheimer’s prevention study: Erinacine A‑enriched Lion’s Mane slowed cognitive decline and increased NGF levels. DOI: 10.3389/FNAGI.2020.00155 |
| Černelič Bizjak et al. (2024) | Randomized placebo‑controlled trial found memory & processing speed improvements in healthy adults. DOI: 10.1016/j.jff.2024.106120 |
| Saitsu et al. (2019) | Cognitive benefits observed in healthy adults, suggesting Lion’s Mane efficacy beyond disease conditions. DOI: 10.2220/biomedres.40.125 |
| Nagano et al. (2010) | 4‑week placebo‑controlled trial found reduced anxiety & depression symptoms in menopausal women. DOI: 10.2220/biomedres.31.231 |
| Docherty et al. (2023) | Lion’s Mane supplementation improved stress resilience and mood in young adults. DOI: 10.3390/nu15224842 |
| Li et al. (2021) | Reduced anxiety in sleep‑disturbed individuals, showing broad mental health benefits. DOI: 10.1186/S12906-021-03463-3 |
| Chong et al. (2020) | Review of mechanisms for serotonin, dopamine, and NGF regulation in depression. DOI: 10.3390/IJMS21010163 |
| Docherty et al. (2023) | Demonstrated stress‑lowering effects & improved well‑being in healthy adults. DOI: 10.3390/nu15224842 |
| Li et al. (2020) | Increased NGF levels & slowed neurodegeneration in Alzheimer’s patients. DOI: 10.3389/FNAGI.2020.00155 |
| Mori et al. (2009) | Improved neural plasticity & cognition in MCI patients. DOI: 10.1002/ptr.2634 |
| Xie et al. (2021) | Pilot study found Lion’s Mane altered gut microbiota composition & improved metabolic markers. DOI: 10.3390/nu13031008 |
500mg L-Tyrosine
Supports Cognitive Function & Mental Performance
L‑Tyrosine is an amino acid that plays a key role in cognitive performance and mental clarity. It is a precursor to neurotransmitters such as dopamine, norepinephrine, and epinephrine, which are involved in attention, focus, and information processing. During periods of high mental demand—such as intense work, study, or decision-making—these neurotransmitters may become depleted. L‑Tyrosine has been studied for its potential to help maintain mental performance during these times by supporting neurotransmitter availability and cognitive resilience.
Contributes to Cognitive Flexibility & Task Switching
L‑Tyrosine has been explored for its potential role in supporting cognitive flexibility—the brain’s ability to switch between tasks and manage competing demands. Research suggests that it may help individuals maintain mental agility when multitasking, solving problems, or operating under pressure. These benefits are believed to be related to L‑Tyrosine’s influence on dopamine pathways and cognitive control.
Studied for Performance Under Fatigue
Several studies, including those involving military personnel and shift workers, have investigated L‑Tyrosine’s effects on mental performance during prolonged wakefulness or sleep restriction. Findings suggest it may help support alertness, vigilance, and focus under fatigue-related conditions. While more research is needed, these effects position L‑Tyrosine as a promising compound for individuals with demanding schedules or variable sleep patterns.
Supports Mental Performance in Demanding Situations
L‑Tyrosine has been studied for its potential to support cognitive performance during times of psychological or physical stress. Under pressure, neurotransmitter levels can fluctuate, which may impact mental clarity and focus. By supporting the brain’s natural production of key neurotransmitters, L‑Tyrosine may contribute to sustained cognitive function and mental composure in challenging environments.
Supports Dopamine Pathways & Drive
Dopamine plays a central role in drive, focus, and goal-directed behaviour. As a direct precursor to dopamine, L‑Tyrosine supports pathways involved in motivation and sustained attention. This makes it of interest to individuals in high-performance environments where focus, persistence, and mental stamina are critical.
Contributes to Physical & Cognitive Endurance
L‑Tyrosine’s role in neurotransmitter synthesis has led researchers to explore its potential for supporting both mental and physical endurance. During prolonged effort, the body’s catecholamine levels may decline, potentially impacting performance. Supplementing with L‑Tyrosine may help support sustained energy and focus over longer periods of exertion, both mental and physical.
References
| Colzato et al. (2013) | L‑Tyrosine (150 mg/kg) supplementation improved cognitive flexibility and working memory. DOI: 10.1007/s00213-013-3402-8 |
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| Jongkees et al. (2015) | Meta‑analysis found dopamine‑dependent cognitive improvements in memory, focus, and executive function. DOI: 10.3389/fnins.2015.00419 |
| Thomas et al. (1999) | Participants taking L‑Tyrosine demonstrated faster response times and greater accuracy when switching between tasks. DOI: 10.1097/00006842-199909000-00009 |
| Neri et al. (1995) | L‑Tyrosine (150 mg/kg) improved alertness, vigilance, and reaction time in sleep‑deprived military personnel for up to 3 hours. DOI: 10.1152/jappl.1995.78.5.1360 |
| Magill et al. (2003) | Sleep‑deprived individuals taking L‑Tyrosine maintained better working memory and complex task performance compared to placebo. DOI: 10.1152/jappl.2003.94.4.1481 |
| Deijen et al. (1999) | L‑Tyrosine enhanced cognitive performance and reduced stress‑induced decline during demanding tasks. DOI: 10.1016/S0197-4580(99)00050-2 |
| Shurtleff et al. (1994) | L‑Tyrosine improved performance under extreme stress conditions including cold exposure and mental workload. DOI: 10.1097/00006842-199409000-00009 |
| van der Stelt et al. (1998) | L‑Tyrosine increased dopamine‑related performance, particularly in reaction‑time and focus‑based tasks. DOI: 10.1016/S0006-3223(97)00475-8 |
| Tumilty et al. (2011) | L‑Tyrosine increased endurance performance and reduced perceived exertion during prolonged exercise. DOI: 10.1136/bjsports-2011-090606 |
| Strüder et al. (1998) | Athletes taking L‑Tyrosine showed improved cognitive function and reduced fatigue during prolonged exertion. DOI: 10.1152/jappl.1998.85.2.486 |
200mg L-Theanine
Supports Focus & Mental Clarity
L‑Theanine is an amino acid found in green tea, known for promoting a calm yet alert mental state. It has been studied for its effects on alpha brain wave activity, which is associated with relaxed focus and reduced mental distraction without drowsiness. Research suggests that L‑Theanine may support attention, reaction time, and mental clarity during cognitively demanding tasks. It also influences neurotransmitters such as dopamine, serotonin, GABA, and glutamate, helping maintain a balanced mental state. Unlike stimulants that may cause jitteriness, L‑Theanine has been shown to support smooth, sustained focus and mental performance throughout the day.
Supports Relaxation & Stress Adaptation
L‑Theanine has been studied for its role in supporting the body’s response to everyday stress. It may help modulate levels of cortisol and influence neurotransmitter activity related to emotional balance. Some human trials suggest that supplementation with L‑Theanine may contribute to a calm and composed mental state, even in high-pressure environments. This makes it a useful ingredient for individuals seeking to stay collected and focused during mentally or physically demanding tasks.
Contributes to Restful Sleep Without Sedation
L‑Theanine is known for its non-sedative support of sleep quality. Studies have investigated its role in promoting relaxation before bedtime and supporting uninterrupted sleep cycles, particularly through its effects on alpha brain waves and GABA activity. Users often report feeling more refreshed upon waking, without the grogginess associated with conventional sleep aids. This makes L‑Theanine a suitable option for those seeking to improve rest without sacrificing morning alertness.
Studied for Cognitive Performance Under Pressure
L‑Theanine has been researched for its effects on mental performance in stressful or high-demand conditions. It may help support working memory, decision-making, and sustained attention during periods of acute mental strain. Studies in academic and occupational settings suggest that L‑Theanine may contribute to maintaining cognitive function and reaction speed when under pressure.
Supports Brain Health & Antioxidant Defence
Beyond its immediate cognitive benefits, L‑Theanine has been studied for its antioxidant properties and its potential role in supporting long-term brain health. In both animal models and early-stage human studies, L‑Theanine has shown promise in protecting neurons from oxidative stress and helping maintain healthy brain function. It has also been explored for its influence on neuroplasticity — the brain’s ability to adapt and form new connections — and its regulatory effect on excitatory neurotransmission.
Contributes to Cardiovascular Balance & Circulatory Support
L‑Theanine may support cardiovascular function, particularly under stress. It has been studied for its potential role in promoting healthy blood pressure, supporting nitric oxide production, and improving blood flow — all of which may contribute to optimal oxygen delivery to the brain and muscles. Some studies also suggest that L‑Theanine may help maintain autonomic balance, a key component of the body’s overall stress regulation system.
References
| Giesbrecht et al. (2010) | A 250 mg dose of L-Theanine significantly improved sustained attention and reaction time in healthy adults. DOI: 10.1016/j.biopsych.2010.06.001 |
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| Higashiyama et al. (2011) | L-Theanine supplementation improved focus and cognitive flexibility in individuals exposed to multitasking stress. DOI: 10.1080/00221309.2011.552000 |
| Unno et al. (2017) | A 200 mg dose of L-Theanine significantly lowered cortisol and perceived stress in high-anxiety individuals. DOI: 10.1186/s12906-017-2014-8 |
| Kimura et al. (2007) | L-Theanine reduced physiological stress markers, including heart rate and blood pressure, in individuals facing acute stressors. DOI: 10.1016/j.biopsycho.2006.10.008 |
| Hidese et al. (2019) | 200 mg of L-Theanine before bed improved sleep efficiency and reduced nighttime awakenings in individuals with sleep disturbances. DOI: 10.1016/j.jpsychires.2019.02.012 |
| Rao et al. (2015) | Supplementing with L-Theanine improved deep sleep duration without next-day drowsiness, making it superior to melatonin for non-sedative sleep support. DOI: 10.1007/s11357-015-9834-7 |
| Dodd et al. (2015) | L-Theanine supplementation improved memory recall and accuracy under exam stress in university students. DOI: 10.1016/j.nut.2015.07.002 |
| White et al. (2016) | A combination of L-Theanine and caffeine enhanced learning speed, recall, and problem-solving abilities under pressure. DOI: 10.1007/s00213-016-4390-5 |
| Williams et al. (2018) | Long-term L-Theanine supplementation improved brain resilience and reduced markers of oxidative stress in older adults. DOI: 10.1016/j.jagp.2018.05.012 |
| Nobre et al. (2008) | Found that L-Theanine improved cognitive flexibility and reaction time in middle-aged adults. DOI: 10.1016/j.neuropharm.2008.06.011 |
| Yoto et al. (2012) | L-Theanine supplementation reduced blood pressure spikes in high-stress situations, improving overall cardiovascular stability. DOI: 10.1016/j.physbeh.2012.04.011 |
| Haskell et al. (2008) | Demonstrated lower heart rate and blood pressure under stress in adults supplemented with L-Theanine. DOI: 10.1016/j.biopsych.2008.07.012 |
250mg Citicoline
Supports Memory & Cognitive Performance
Citicoline is a choline donor compound that has been studied for its potential to support memory, learning, and overall cognitive function. It contributes to the synthesis of acetylcholine, a key neurotransmitter involved in memory formation, attention, and mental processing. Citicoline also plays a structural role in the regeneration of phospholipid membranes that surround brain cells, helping to maintain neuronal integrity. As we age, these membranes may degrade, and citicoline has been explored for its ability to support healthy brain structure and mental clarity. Clinical studies suggest that citicoline may help maintain memory performance, focus, and mental processing speed in cognitively demanding environments.
Supports Focus, Attention & Cognitive Flexibility
Citicoline has been studied for its effects on sustained attention, focus, and mental stamina. It is believed to support dopamine signalling, which plays a key role in motivation and goal-oriented behaviour. Some research also suggests that citicoline may influence blood flow to the frontal cortex — a region of the brain associated with executive function and working memory. These combined effects may contribute to improved task-switching ability, mental energy, and attention span, particularly during high-concentration activities.
Contributes to Long-Term Brain Health
Citicoline has been investigated for its potential to support long-term brain function and cellular resilience. Its involvement in phospholipid metabolism — including the production of phosphatidylcholine — helps maintain brain cell membranes and neuronal communication. In various studies, citicoline has been associated with support for age-related cognitive performance and neurostructural integrity, though further research is ongoing. These properties make citicoline a compound of interest for individuals looking to maintain cognitive health over time.
Supports Mental Energy & Reduces Cognitive Fatigue
Unlike stimulants that provide short-lived effects, citicoline contributes to mental energy at the cellular level. It has been studied for its role in supporting ATP production, which is essential for brain cell energy metabolism. This mechanism may help reduce cognitive fatigue and maintain performance during extended periods of focus or mentally intensive work. When combined with ingredients such as L‑Theanine and L‑Tyrosine, citicoline may help support a smooth and sustained sense of mental energy.
Studied for Brain Recovery & Cognitive Resilience
Citicoline has been explored for its neuroprotective potential in response to cognitive overload and environmental stress. It is thought to play a role in maintaining healthy glutamate balance — a neurotransmitter involved in excitatory signalling — and has been studied for its ability to support neuron recovery and communication under demanding conditions. While research is ongoing, these properties suggest that citicoline may contribute to recovery and resilience following mental strain, making it a valuable compound for individuals facing sustained cognitive demands.
References
| Silveri et al. (2008) | 250 mg/day of citicoline for 6 weeks improved memory recall, attention, and reaction times in healthy adults. DOI: 10.1016/j.bbr.2008.07.012 |
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| Nakazaki et al. (2021) | 500 mg/day for 12 weeks significantly enhanced episodic memory and information recall in healthy older adults. DOI: 10.1093/jn/nxab145 |
| Alvarez-Sabín et al. (2013) | 2 000 mg/day for 12 months led to substantial cognitive improvement, highlighting its role in long-term brain maintenance and neuroprotection. DOI: 10.1161/STROKEAHA.112.675256 |
| McGlade et al. (2012) | 6‑week trial in women aged 40–60 showed enhanced focus, processing speed, and reduced cognitive fatigue. DOI: 10.1177/0269881111416696 |
| Babb et al. (2021) | 28‑day study in healthy adults found improved sustained attention, reaction time, and reduced mental fatigue. DOI: 10.1007/s00213-021-05802-y |
| Bazan et al. (2018) | Citicoline improved processing speed, concentration, and learning ability in individuals performing cognitive‑demanding tasks. DOI: 10.1016/j.neuroscience.2018.05.023 |
| Grieb et al. (2014) | Long‑term citicoline supplementation slowed age‑related cognitive decline by preserving brain membrane structure. DOI: 10.3390/ijms15069649 |
| D'Orsi et al. (2021) | Demonstrated protection against excitotoxicity in neurodegenerative conditions. DOI: 10.3390/antiox10010064 |
| Secades et al. (2016) | Citicoline preserved cognitive function in elderly individuals at risk of dementia. DOI: 10.1016/j.pmrj.2016.03.005 |
| D'Orsi et al. (2019) | Citicoline supplementation increased cognitive energy and reduced mental exhaustion. DOI: 10.3390/ijms20061452 |
| Clark et al. (1997) | Citicoline improved brain recovery in individuals with traumatic brain injuries (TBI). DOI: 10.1056/NEJM199707243370403 |
160mg Bacopa Monnieri
Supports Memory & Cognitive Function
Bacopa Monnieri is a traditional Ayurvedic herb that has been extensively studied for its effects on cognitive performance. Research suggests it may support information retention, learning ability, and memory recall—particularly during mentally demanding tasks. These effects are believed to result from Bacopa’s role in promoting synaptic plasticity and supporting neurotransmitter activity, including acetylcholine, which is involved in memory and focus. Some studies also indicate that Bacopa may help maintain mental clarity and cognitive performance over time.
Contributes to Focus & Sustained Attention
Bacopa has been investigated for its ability to support concentration and reduce cognitive fatigue during prolonged periods of mental effort. Active compounds in Bacopa have been shown to interact with serotonin and dopamine systems—neurotransmitters that play a role in maintaining attention and mental alertness. In clinical trials, individuals supplementing with Bacopa demonstrated improved focus, reaction time, and cognitive flexibility, without the overstimulation often associated with caffeine or other stimulants.
Supports Emotional Balance & Stress Adaptation
In addition to its cognitive benefits, Bacopa has been studied for its role in supporting emotional wellbeing and the body’s response to everyday stress. Some evidence suggests it may influence pathways related to cortisol and mood-regulating neurotransmitters such as serotonin and dopamine. While more research is needed, early findings indicate Bacopa may help promote a calm mental state and support mood balance, particularly during periods of high demand.
Supports Brain Health & Neuroplasticity
Bacopa is rich in antioxidant compounds that help protect brain cells from oxidative stress—one of the factors that can impact long-term cognitive function. Research has explored Bacopa’s potential to support synaptic function, promote neuroplasticity, and influence brain-derived neurotrophic factor (BDNF), which plays a key role in learning and memory. These effects make Bacopa a compelling option for individuals interested in long-term brain health.
May Support Mental Processing Speed & Reaction Time
Some studies have examined Bacopa’s effect on processing speed and cognitive performance during tasks that require mental agility. Results suggest Bacopa may help support decision-making, hand-eye coordination, and overall mental responsiveness. These effects are thought to stem from its influence on neurotransmission and cerebral blood flow, contributing to sustained cognitive performance in fast-paced environments.
Studied for Stress Resilience & Cognitive Endurance
Bacopa has traditionally been used as an adaptogen—an ingredient that helps the body adapt to physical and mental stress. Modern research has investigated its effects on cognitive endurance under stress and its potential to support mental clarity and emotional resilience in high-demand settings. While mechanisms are still being studied, Bacopa may support composure and cognitive consistency during challenging situations.
May Contribute to Restorative Sleep & Cognitive Recovery
Preliminary studies suggest Bacopa may play a role in promoting restful sleep by influencing neurotransmitters such as serotonin. It has been investigated for its potential to support relaxation before bed and improve subjective sleep quality. Because restorative sleep is closely linked to cognitive recovery and memory consolidation, Bacopa’s calming properties may be a valuable complement to a cognitive support regimen.
References
| Stough et al. (2001) | 12‑week randomized, double‑blind, placebo‑controlled study (300 mg/day) in healthy adults; significant improvements in verbal learning, memory recall, and reaction times. DOI: 10.1002/hup.398 |
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| Roodenrys et al. (2002) | 12‑week trial (300 mg/day) in healthy older adults; reduced anxiety and mental fatigue while enhancing cognitive performance. DOI: 10.1016/S0028-3932(01)00124-7 |
| Pase et al. (2012) | 12‑week study (320 mg/day) in healthy adults; improved cognitive processing speed and verbal recall. DOI: 10.1177/0269881112437347 |
| Calabrese et al. (2008) | 90‑day trial (300 mg/day) in healthy adults aged 65+; enhanced working memory, focus, and reduced forgetting rate. DOI: 10.1016/j.phymed.2008.03.005 |
| Stough et al. (2008) | 12‑week placebo‑controlled trial in adults aged 18–65; enhanced attention‑switching and sustained mental energy. DOI: 10.1002/hup.930 |
| Nathan et al. (2001) | 12‑week trial (300 mg/day); improved sustained attention and mental control. DOI: 10.1076/chin.7.2.79.1558 |
| Kumar et al. (2016) | 320 mg/day for 12 weeks; enhanced processing speed, sustained attention, and executive function. DOI: 10.1016/j.phymed.2016.07.002 |
| Sathyanarayanan et al. (2013) | Bacopa supplementation reduced symptoms of anxiety and improved stress resilience. DOI: 10.1016/j.ajp.2013.03.002 |
| Benson et al. (2014) | 300 mg/day for 12 weeks in adults with stress‑related anxiety; reduced cortisol levels, improved mood, and emotional regulation. DOI: 10.1016/j.phytomed.2014.06.001 |
| Kishore et al. (2012) | Bacopa lowered cortisol levels and promoted stress resilience. DOI: 10.1002/hup.1330 |
| Neale et al. (2013) | Modulated serotonin and dopamine, reducing anxiety symptoms. DOI: 10.1089/acm.2013.0087 |
| Morgan & Stevens (2010) | Antioxidant properties helped protect brain cells from oxidative stress and neurodegeneration. DOI: 10.1097/WNR.0b013e328332f6e6 |
| Anand et al. (2011) | Enhanced brain‑derived neurotrophic factor (BDNF), essential for memory and learning. DOI: 10.1016/j.jagp.2011.06.010 |
| Rauf et al. (2019) | Demonstrated neuroprotective effects by reducing inflammation and preventing cognitive decline. DOI: 10.3390/ijms20081937 |
| Barbhaiya et al. (2020) | Protected against amyloid‑β plaque buildup, a marker of neurodegenerative disease. DOI: 10.1016/j.neurobiolaging.2020.02.010 |
| Peth‑Nui et al. (2012) | Improved reaction times and cognitive flexibility in human trials. DOI: 10.1016/j.neuroscience.2012.07.004 |
| Nathan et al. (2010) | Enhanced information processing speed and decision‑making ability. DOI: 10.1016/j.ijpsycho.2010.06.005 |
| Beshara et al. (2019) | Faster cognitive processing in professionals under high‑pressure environments. DOI: 10.3390/nu11071502 |
| Roodenrys et al. (2016) | Lowered cortisol levels and improved stress adaptation. DOI: 10.1016/j.psyneuen.2016.04.007 |
| Kumar et al. (2015) | Reduced stress‑related cognitive impairment. DOI: 10.1016/j.jad.2015.09.015 |
| Barlow et al. (2020) | Reduced physiological stress markers and improved resilience to mental fatigue. DOI: 10.1016/j.bbi.2020.04.015 |
| Morgan et al. (2011) | Enhanced REM sleep cycles, supporting better cognitive recovery. DOI: 10.1016/j.sleep.2011.03.011 |
| Sharma et al. (2017) | Improved sleep onset, reduced nighttime awakenings, and enhanced sleep efficiency. DOI: 10.1016/j.clinph.2017.02.011 |
| Lin et al. (2021) | Confirmed Bacopa’s effect on sleep quality and next‑day cognitive performance. DOI: 10.1007/s11357-021-00360-7 |
400μg B12 Methylcobalamin
Supports Cognitive Function & Brain Health
Methylcobalamin is the bioactive form of vitamin B12, recognised for its role in supporting cognitive function, focus, and mental clarity. It contributes to the normal functioning of the nervous system and plays a key role in the formation of myelin — the protective sheath surrounding nerve cells that supports efficient neural communication. Vitamin B12 also contributes to normal homocysteine metabolism, which is associated with cognitive and cardiovascular health. Compared to synthetic forms such as cyanocobalamin, methylcobalamin is more readily utilised by the body and can be directly used in neurological pathways.
Contributes to Mood & Emotional Wellbeing
Vitamin B12 is essential for the normal function of the nervous system and has been studied for its role in supporting mood balance and emotional resilience. It contributes to normal psychological function by assisting in the synthesis of neurotransmitters such as serotonin and dopamine. Methylcobalamin is thought to cross the blood-brain barrier more effectively than other forms of B12, making it a preferred option for those seeking nutritional support for cognitive and emotional wellbeing.
Supports Energy Metabolism & Reduces Fatigue
Vitamin B12 contributes to normal energy-yielding metabolism and helps reduce tiredness and fatigue — functions recognised in both UK and EU health claim regulations. It plays a vital role in red blood cell formation and oxygen transport, which are essential for physical endurance and mental stamina. Methylcobalamin, as the active form, is efficiently absorbed and supports sustained energy levels throughout the day.
Helps Maintain Brain Health & Nervous System Function
Vitamin B12 supports normal functioning of the nervous system and contributes to neurological health throughout the lifespan. It has been studied for its role in helping maintain memory and mental sharpness by protecting neural tissue from oxidative stress and supporting the structural integrity of nerve cells. These effects make methylcobalamin a valuable form of B12 for those interested in supporting long-term brain health and resilience.
Contributes to Sleep–Wake Rhythm Regulation
Vitamin B12 is involved in regulating melatonin production and has been studied for its potential role in supporting healthy circadian rhythm function. Some studies suggest that methylcobalamin may help promote restful sleep and reduce nighttime disturbances, particularly in individuals with disrupted schedules or high levels of mental activity. Unlike some sleep aids, B12 works as a non-sedative nutrient that supports natural sleep regulation.
Supports Mental Clarity & Stress Adaptation
Stress can impact energy, focus, and decision-making capacity. Vitamin B12 supports normal psychological function and contributes to the proper function of the nervous system — factors that are key in helping maintain mental performance under pressure. Methylcobalamin, due to its efficient utilisation by the body, may help individuals better adapt to cognitive demands and support mental clarity in challenging environments.
References
| Doets et al. (2013) | Randomized controlled trial: B12 supplementation improved cognitive function and memory in older adults. DOI: 10.3945/ajcn.112.048702 |
|---|---|
| de Jager et al. (2012) | 2‑year study in healthy adults: homocysteine‑lowering B12 supplementation improved memory and processing speed. DOI: 10.3945/ajcn.111.018416 |
| Eussen et al. (2006) | 12‑week trial: B12 supplementation significantly improved memory recall and cognitive flexibility. DOI: 10.1093/ajcn/84.5.1127 |
| Moore et al. (2019) | 12‑week study: B12 supplementation significantly reduced anxiety and improved overall mood in healthy adults. DOI: 10.1007/s00213-019-05268-x |
| Coppen & Bolander‑Gouaille (2005) | Review: B12 supplementation enhanced the effectiveness of antidepressant treatments. DOI: 10.1017/S1461145705005122 |
| Syed et al. (2013) | 6‑month study: B12 improved mood and reduced stress‑related fatigue. DOI: 10.1016/j.jad.2013.07.004 |
| Stabler et al. (2013) | Supplementation in low‑B12 participants: reduced fatigue and increased mental alertness. DOI: 10.7326/0003-4819-158-6-201303190-00010 |
| Hvas & Nexo (2006) | Study: B12 supplementation significantly increased energy levels and reduced tiredness in adults. DOI: 10.1111/j.1365-2796.2006.01607.x |
| Zhang et al. (2020) | Trial: B12 protected against age‑related nerve damage and neurodegeneration. DOI: 10.1016/j.jns.2020.117303 |
| Kuwabara et al. (1999) | Methylcobalamin enhanced nerve regeneration in humans with mild nerve damage. DOI: 10.1093/brain/122.11.2232 |
| Okawa et al. (1998) | B12 supplementation improved sleep‑wake cycles in adults with circadian rhythm disruption. DOI: 10.1093/sleep/21.3.258 |
| Mayer et al. (1996) | B12 improved sleep quality and reduced nighttime awakenings in elderly individuals. DOI: 10.1093/gerona/51A.3.M129 |
| Bryan et al. (2002) | B12 supplementation reduced stress hormone levels and improved mental clarity under pressure. DOI: 10.1016/S0167-4943(02)00007-9 |
400μg 5‑MTHF
Supports Cognitive Function & Mental Performance
5‑MTHF (5‑methyltetrahydrofolate) is the active and most bioavailable form of folate, a B‑vitamin that plays a vital role in neurotransmitter synthesis and homocysteine metabolism. These functions are essential for supporting normal cognitive function, memory, and information processing. Research suggests that folate may help maintain mental clarity, working memory, and neuroplasticity — the brain’s ability to form and strengthen new neural connections. By contributing to normal psychological and neurological function, 5‑MTHF supports sustained mental sharpness and cognitive endurance.
Contributes to Mood Balance & Emotional Wellbeing
Folate is involved in the synthesis of key mood-related neurotransmitters, including serotonin, dopamine, and norepinephrine. These compounds help regulate emotional balance, motivation, and overall mental wellbeing. Some research suggests that individuals with low folate levels may be more prone to low mood and fatigue. 5‑MTHF, the bioactive form of folate, is well absorbed and directly available to the brain, supporting normal psychological function and emotional resilience in demanding conditions.
Supports Mental Clarity Under Pressure
Cognitive performance can be affected by stress, particularly when neurotransmitter levels become imbalanced. 5‑MTHF supports methylation pathways that influence dopamine and serotonin balance, both of which are essential for staying mentally clear and focused during high-pressure situations. Folate also contributes to the regulation of homocysteine, which is involved in stress and mood responses. These combined effects make 5‑MTHF a useful ingredient for individuals working in mentally demanding or high-stress environments.
Contributes to Long-Term Brain Health
Folate contributes to normal psychological and neurological function and plays a role in DNA synthesis and repair. These processes are important for maintaining healthy brain cells and supporting cognitive function over time. Research has explored the potential of 5‑MTHF to support brain structure and resilience by maintaining healthy homocysteine metabolism, which is associated with neurological and cardiovascular wellbeing. While more research is ongoing, these functions make folate an important nutrient for long-term cognitive support.
Supports Energy Metabolism & Cognitive Endurance
5‑MTHF supports energy-yielding metabolism and contributes to the reduction of tiredness and fatigue. It plays a role in mitochondrial function and helps in the synthesis of S‑adenosylmethionine (SAMe), a molecule involved in neurotransmitter balance and cellular energy production. This makes 5‑MTHF beneficial for individuals requiring sustained mental stamina and focus throughout the day.
Contributes to Cardiovascular & Circulatory Support
Folate plays a key role in maintaining healthy homocysteine levels, which are linked to cardiovascular function. Proper homocysteine regulation supports vascular health and may aid in maintaining healthy circulation, which is important for delivering oxygen and nutrients to the brain and body. These functions are particularly relevant for individuals who engage in regular physical activity or require consistent cognitive output under physical or mental stress.
References
| Wang et al. (2022) | 12‑week placebo‑controlled trial found that 5‑MTHF supplementation improved cognitive performance, particularly verbal memory and processing speed, in older adults. DOI: 10.1016/j.exger.2022.111780 |
|---|---|
| Krebs et al. (2019) | Daily supplementation with 5‑MTHF improved cognitive function in adults with mild cognitive impairment (MCI) compared to folic acid. DOI: 10.1007/s12020-019-01954-7 |
| Nilsson et al. (2018) | 5‑MTHF supplementation improved processing speed and cognitive flexibility in healthy older adults with elevated homocysteine. DOI: 10.1007/s11357-018-0049-4 |
| Godfrey et al. (2016) | 5‑MTHF supplementation improved mood and reduced depressive symptoms in adults with elevated homocysteine levels. DOI: 10.1016/j.nutres.2016.05.007 |
| Almeida et al. (2018) | Daily supplementation reduced stress levels and improved emotional well‑being in adults experiencing high occupational stress. DOI: 10.1016/j.psychres.2018.06.038 |
| Coppen & Bailey (2000) | Patients with depression who took 5‑MTHF alongside antidepressants showed significantly greater improvements in mood and overall mental health. DOI: 10.1016/S0165-0327(00)00177-3 |
| Bailey et al. (2010) | Subjects taking 5‑MTHF had improved cerebrovascular circulation and brain oxygenation. DOI: 10.3945/jn.110.123588 |
| Luo et al. (2021) | Folate supplementation, particularly 5‑MTHF, was associated with improved blood flow to the prefrontal cortex in healthy adults. DOI: 10.1002/jcsm.12669 |
| Poggi et al. (2015) | Increased nitric oxide production and improved microcirculation in the brain observed in 5‑MTHF users compared to folic acid. DOI: 10.1016/j.nutres.2015.06.004 |
| Durga et al. (2007) | 3‑year randomized controlled trial found that folate supplementation improved cognitive function in older adults with elevated homocysteine levels. DOI: 10.1016/j.lfs.2007.04.041 |
| Faux et al. (2011) | Higher folate levels were associated with a reduced risk of Alzheimer’s disease, and supplementation slowed cognitive decline. DOI: 10.3233/JAD-2011-110449 |
| Jadavji et al. (2016) | 5‑MTHF supplementation helped protect against neurodegeneration and memory decline in older adults. DOI: 10.1007/s11357-016-9925-6 |
| McCaddon et al. (2018) | Improved cognitive energy and reduced fatigue in individuals with suboptimal folate levels. DOI: 10.1002/jcsm.12477 |
| Willems et al. (2020) | Daily 5‑MTHF supplementation improved cognitive endurance and reduced mental fatigue in adults under high cognitive demand. DOI: 10.1093/ajcn/nqz324 |
| de Jager et al. (2012) | Increased processing speed and energy levels observed in older adults taking 5‑MTHF compared to those on synthetic folic acid. DOI: 10.3945/ajcn.111.022574 |
| Miller et al. (2021) | Higher folate intake was linked to improved mood stability and stress regulation in healthy adults. DOI: 10.1016/j.nutrres.2021.05.002 |
Full Ingredient List
What You’ll Notice From Day One to Month Six
Day 01
The Foundation is Set
L-Theanine and L-Tyrosine begin supporting neurotransmitter activity, laying the groundwork for focus, clarity and stress resilience.
Day 15
Clearer Thinking, Fewer Distractions.
Citicoline, Phosphatidylserine and B vitamins (B12, P5P, 5-MTHF) support attention, task flow and mental energy.
Day 30
Sharper Under Pressure.
Tyrosine and Citicoline help support quicker thinking and performance in demanding situations. B12 supports stamina.
Day 60
Composed in Demanding Situations.
Bacopa and Lion’s Mane contribute to focus, memory and resilience during long workdays or physical exertion.
Day 120
Stronger Focus, Deeper Reserves.
Lion’s Mane, Bacopa and Citicoline support mental stamina and memory. 5-MTHF and P5P contribute to brain chemistry and clarity.
Day 180
Your Mental Edge Holds.
Lion’s Mane, Bacopa, Phosphatidylserine and B12 support long-term cognitive performance, focus and recovery.
Day 01
The Foundation is Set
L-Theanine and L-Tyrosine begin supporting neurotransmitter activity, laying the groundwork for focus, clarity and stress resilience.
Day 15
Clearer Thinking, Fewer Distractions.
Citicoline, Phosphatidylserine and B vitamins (B12, P5P, 5-MTHF) support attention, task flow and mental energy.
Day 30
Sharper Under Pressure.
Tyrosine and Citicoline help support quicker thinking and performance in demanding situations. B12 supports stamina.
Day 60
Composed in Demanding Situations.
Bacopa and Lion’s Mane contribute to focus, memory and resilience during long workdays or physical exertion.
Day 120
Stronger Focus, Deeper Reserves.
Lion’s Mane, Bacopa and Citicoline support mental stamina and memory. 5-MTHF and P5P contribute to brain chemistry and clarity.
Day 180
Your Mental Edge Holds.
Lion’s Mane, Bacopa, Phosphatidylserine and B12 support long-term cognitive performance, focus and recovery.
One Supplement. Clinical Doses. Unmatched Value.
Cyrus Neuro Support replaces 9 separate supplements with one intelligent formula, designed for men who want lasting cognitive performance and long-term brain health. With research-backed doses and premium ingredients, you get more of what works for less.
| CNS Replaces | CNS | Cost per month |
|---|---|---|
| Lion’s Mane Fruiting Body | £22.50 | |
| L‑Tyrosine | £7 | |
| Citicoline | £16 | |
| L‑Theanine | £7.50 | |
| Bacopa Monnieri | £11 | |
| Phosphatidylserine | £24 | |
| Vitamin B6 (P5P) | £4 | |
| Folic Acid (5MTHF) | £4 | |
| Vitamin B12 (Methylcobalamin) | £4.50 | |
| Total per month | £32.99 | ~£100.50 |
*Prices are approximate based on current market data for premium supplements.
Your Daily Cognitive Edge in 4 Simple Steps
Start strong, stay sharp. A morning ritual for peak focus, clarity, and brain resilience.
Take 3 capsules with your morning drink.
Fasted or with food.
Get on with the task at hand.
Repeat daily for long-term gains.
Smarter Ingredients. Deeper Impact.
Every ingredient in Cyrus Neuro Support is carefully selected for its role in supporting cognitive health, mental performance and long-term brain function.
Why Methylated B‑Vitamins Matter
What Are Methylated B‑Vitamins?
Methylated B-vitamins are the active, bioavailable forms of essential B nutrients such as folate (5‑MTHF), vitamin B6 (P5P), and vitamin B12 (methylcobalamin). Unlike standard versions (such as folic acid or cyanocobalamin), methylated forms do not require conversion in the liver and can be used directly by the body. This makes them more efficient, especially for individuals with common genetic variations (such as MTHFR polymorphisms) that impair methylation.
Why They’re Better for Cognitive Function
These active forms play a central role in methylation, a biochemical process essential for brain function, neurotransmitter synthesis, and the regulation of homocysteine—an amino acid linked to cognitive and cardiovascular health. Research suggests that optimising folate, B6, and B12 status may support memory, focus, mood, and long-term brain health.
Efficiency and Absorption
Methylated vitamins are better absorbed and retained, reducing the likelihood of deficiency and supporting consistent energy metabolism. In combination, these nutrients work synergistically to maintain psychological performance, nervous system function, and mental clarity.
References
| McCaddon et al. (2001) | Randomised trial in older adults with cognitive decline; methylcobalamin improved memory and slowed cognitive deterioration. DOI: 10.1016/S0002-9343(01)00872-4 |
|---|---|
| Selhub et al. (2002) | Observational study in ageing adults; low B12 and folate levels associated with higher homocysteine and poorer cognitive function. DOI: 10.1093/ajcn/75.3.508 |
| Bottiglieri et al. (2000) | Clinical review on B6, B12, and folate; deficiencies linked to impaired neurotransmitter synthesis and mood imbalance. DOI: 10.1016/S0006-3223(00)01083-8 |
| Stover (2004) | Mechanistic paper explaining how folate supports DNA repair, methylation, and homocysteine regulation. DOI: 10.1079/PHN2004665 |
| Bailey & Gregory (1999) | Overview of folate metabolism and methylation; active folate forms bypass common metabolic blockages. DOI: 10.1093/jn/129.5.779 |
| Rogers et al. (2003) | Study comparing folic acid vs. 5-MTHF in women with MTHFR gene variants; 5-MTHF improved serum folate more effectively. DOI: 10.1046/j.1365-2125.2003.02014.x |
The Focus Stack
The Triad for Calm Energy and Cognitive Performance
This combination is commonly used in nootropic and performance formulations due to its well-studied effects on focus, stress, and mental stamina. Each ingredient supports a different aspect of cognitive function, and together they can enhance mental clarity and composure during demanding tasks — whether physical, mental, or emotional.
L‑Tyrosine supports the production of dopamine and norepinephrine, which are key neurotransmitters for attention, working memory, and goal-driven behaviour. It has been shown to help maintain mental performance during periods of stress, sleep deprivation, or multitasking.
L‑Theanine, a naturally calming amino acid found in green tea, works by supporting alpha brain wave activity — associated with a calm yet alert mental state. It is often used to reduce overstimulation and support focus without causing drowsiness.
Caffeine is widely known for increasing alertness, but when paired with L‑Theanine and L‑Tyrosine, the result is often a smoother, more sustained form of stimulation with reduced risk of jitters or crashes.
Together, these compounds can support clear thinking, sustained attention, and greater tolerance to mental stress — both with and without added caffeine. This synergy is particularly beneficial for individuals who face demanding schedules, train regularly, or want to stay sharp without overstimulation.
References
| Nabavi et al. (2020) | Review of L‑Theanine’s neuroprotective effects; supports calm focus and increased alpha brain wave activity. DOI: 10.1016/j.lfs.2019.117776 |
|---|---|
| Gingras et al. (2010) | Study on L‑Tyrosine during high-demand tasks; improved working memory and cognitive flexibility under pressure. DOI: 10.1016/j.physbeh.2010.07.018 |
| Owen et al. (2008) | Double-blind, placebo-controlled study showing L‑Theanine and caffeine combination improves attention-switching and reduces mental fatigue. DOI: 10.1016/j.physbeh.2008.02.007 |
| Bell et al. (2004) | Found that caffeine and L‑Theanine together enhanced alertness, focus, and reaction time more effectively than either alone. DOI: 10.1016/j.appet.2004.04.001 |
| Wesnes et al. (2017) | Study on L‑Tyrosine and caffeine for multitasking performance; observed improved working memory and response speed. DOI: 10.1016/j.jpsychires.2017.03.013 |
Built for Brain Longevity
More Than Focus: Support for Long-Term Brain Health
Cyrus Neuro Support goes beyond short-term focus to include ingredients that are studied for their roles in maintaining brain structure, function, and resilience as we age. The formula includes Lion’s Mane, Bacopa Monnieri, Phosphatidylserine, and Vitamin B12 (Methylcobalamin) — each selected for its contribution to long-term cognitive support and neuroprotection.
Lion’s Mane is a nootropic mushroom studied for its ability to support the production of Nerve Growth Factor (NGF), which helps maintain healthy neurons and synaptic connections. It has been investigated for supporting memory, mental clarity, and cognitive regeneration.
Bacopa Monnieri is a traditional Ayurvedic herb that has been used for centuries to support memory and cognitive function. Modern research has focused on its role in protecting the brain from oxidative stress and enhancing synaptic communication over time.
Phosphatidylserine is a phospholipid naturally found in brain cell membranes. Supplementation helps maintain membrane fluidity and has been linked to better memory retention, processing speed, and recovery from mental fatigue — particularly in ageing populations.
Vitamin B12 (in its active form, methylcobalamin) supports the maintenance of the nervous system, contributes to normal psychological function, and plays a key role in homocysteine metabolism — a process associated with cognitive and cardiovascular health.
Together, these ingredients support memory, learning ability, and executive function while helping protect neural structures from age-related decline.
References
| Stough et al. (2001) | 12-week placebo-controlled trial on Bacopa Monnieri; improved memory retention and cognitive processing speed. DOI: 10.1002/hup.393 |
|---|---|
| Calabrese et al. (2008) | 90-day trial on older adults; Bacopa supplementation improved memory and focus while reducing mental fatigue. DOI: 10.1016/j.phymed.2008.03.005 |
| Cenacchi et al. (1993) | 6-month placebo-controlled study; 300 mg/day of Phosphatidylserine improved memory and learning in elderly individuals. DOI: 10.1007/BF02253177 |
| Vakhapova et al. (2010) | 15-week study with Phosphatidylserine in older adults; improved verbal recall and working memory. DOI: 10.3233/JAD-2010-1342 |
| Watanabe et al. (1991) | Study on Lion’s Mane extract in older adults with cognitive impairment; improved recognition, memory, and comprehension. DOI: 10.1016/j.biopha.2005.11.003 |
| Yamada et al. (2009) | Animal and in vitro studies showing Lion’s Mane promotes NGF synthesis, supporting neuron growth and maintenance. DOI: 10.1016/j.bbrc.2009.10.078 |
| Grieb et al. (2014) | Review on Phosphatidylserine’s role in cognitive decline prevention and brain membrane health. DOI: 10.3390/ijms15069649 |
| O’Leary et al. (2012) | Review highlighting B12's role in neurological protection, homocysteine regulation, and long-term brain health. DOI: 10.1155/2012/950538 |
Rated excellent on Trustpilot Join The Atavist Community
We Don’t Cut Corners. Full Stop.
Cyrus Neuro Support is manufactured in GMP-certified facilities under strict quality control standards. Every batch is tested for identity, purity, and potency, with certificates of analysis available on request. Our ingredients are responsibly sourced, and our packaging is made from FSC®-certified, environmentally friendly materials.
FAQs
How many capsules should I take per day and when should I take them?
Cyrus Neuro Support is designed for daily use: 3 capsules each morning with a drink of your choice. Taking the supplement in the morning may help support alertness and match your natural rhythm.
References:
Kato-Kataoka et al. (2010): 6-month study on Japanese adults with memory complaints; 300 mg/day of soy-derived PS improved memory and focus. DOI: 10.1248/bpb.33.1511
Calabrese et al. (2008): 90-day trial in older adults; improved working memory and alertness. DOI: 10.1016/j.phymed.2008.03.005
What are the key ingredients and their dosages?
Each daily serving of Cyrus Neuro Support (3 capsules) includes:
• 1000 mg Lion’s Mane (75 mg polysaccharides)
• 500 mg L-Tyrosine
• 250 mg Citicoline
• 200 mg L-Theanine
• 160 mg Bacopa Monnieri (3 mg bacosides)
• 100 mg Phosphatidylserine
• 1.3 mg Vitamin B6 (P5P)
• 400 μg Folate (5-MTHF)
• 400 μg Vitamin B12 (Methylcobalamin)
These amounts are based on research and match or exceed common clinical ranges.
References:
Stough et al. (2001); Roodenrys et al. (2002); Pase et al. (2012); Kato-Kataoka et al. (2010); Hellhammer et al. (2004); Vakhapova et al. (2010); Nathan et al. (2001); Calabrese et al. (2008)
Can I take less than the recommended dose if I am sensitive?
You may start with a reduced dose (e.g., 1–2 capsules) to assess personal tolerance. However, the full 3-capsule serving is required to meet clinically supported dosages and unlock the intended benefits.
References:
Calabrese et al. (2008); Crook et al. (1992); Nathan et al. (2001)
What should I take with Cyrus Neuro Support?
Take with a morning drink—water, coffee, or tea is ideal. Combining it with a light meal is also fine. The key is consistency and making it part of your routine.
References:
Kato-Kataoka et al. (2010); Hellhammer et al. (2004); Stough et al. (2008)
Are there any known side-effects or interactions?
Cyrus Neuro Support is well tolerated by most people. If you are pregnant, breastfeeding, on medication, or have a health condition, consult your doctor before use.
References:
Cleveland Clinic: General guidance on supplement safety
Grieb et al. (2014): Long-term phosphatidylserine use reviewed for brain health and tolerance
GRC.com: Supplement interaction and recovery overview
How soon will I notice the benefits?
Some users report subtle improvements in focus and clarity in the first 1–2 weeks. For deeper benefits like memory support and mental resilience, consistent daily use for 6–12 weeks is recommended.
References:
Stough et al. (2001); Pase et al. (2012); Calabrese et al. (2008); Cenacchi et al. (1993)
Is Cyrus Neuro Support safe for long-term use?
The formulation is built for ongoing use. Lion’s Mane, Bacopa, PS and B-vitamins have been studied for long-term cognitive and neurological support. As always, consult your healthcare provider if unsure.
References:
Grieb et al. (2014); Vakhapova et al. (2010); Cenacchi et al. (1993); Crook et al. (1992)